COVID-19 (Novel Coronavirus 2019) - recent trends.
Identifieur interne : 000B87 ( Main/Exploration ); précédent : 000B86; suivant : 000B88COVID-19 (Novel Coronavirus 2019) - recent trends.
Auteurs : S. Kannan [Maldives] ; P. Shaik Syed Ali ; A. Sheeza ; K. HemalathaSource :
- European review for medical and pharmacological sciences [ 2284-0729 ] ; 2020.
Descripteurs français
- KwdFr :
- Activation virale, Animaux, Génome viral, Humains, Infections à coronavirus (diagnostic), Infections à coronavirus (épidémiologie), Organisation mondiale de la santé, Pneumopathie virale (diagnostic), Pneumopathie virale (épidémiologie), Protéines nucléocapside (), Protéines nucléocapside (génétique), Protéines nucléocapside (métabolisme).
- MESH :
- diagnostic : Infections à coronavirus, Pneumopathie virale.
- génétique : Protéines nucléocapside.
- métabolisme : Protéines nucléocapside.
- épidémiologie : Infections à coronavirus, Pneumopathie virale.
- Activation virale, Animaux, Génome viral, Humains, Organisation mondiale de la santé, Protéines nucléocapside.
English descriptors
- KwdEn :
- Animals, Betacoronavirus (chemistry), Betacoronavirus (genetics), Betacoronavirus (metabolism), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Genome, Viral, Humans, Nucleocapsid Proteins (chemistry), Nucleocapsid Proteins (genetics), Nucleocapsid Proteins (metabolism), Pneumonia, Viral (diagnosis), Pneumonia, Viral (epidemiology), Virus Activation, World Health Organization.
- MESH :
- chemical , chemistry : Nucleocapsid Proteins.
- chemistry : Betacoronavirus.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- genetics : Betacoronavirus, Nucleocapsid Proteins.
- metabolism : Betacoronavirus, Nucleocapsid Proteins.
- Animals, Genome, Viral, Humans, Virus Activation, World Health Organization.
Abstract
The World Health Organization (WHO) has issued a warning that, although the 2019 novel coronavirus (COVID-19) from Wuhan City (China), is not pandemic, it should be contained to prevent the global spread. The COVID-19 virus was known earlier as 2019-nCoV. As of 12 February 2020, WHO reported 45,171 cases and 1115 deaths related to COVID-19. COVID-19 is similar to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) virus in its pathogenicity, clinical spectrum, and epidemiology. Comparison of the genome sequences of COVID-19, SARS-CoV, and Middle East Respiratory Syndrome coronavirus (MERS-CoV) showed that COVID-19 has a better sequence identity with SARS-CoV compared to MERS CoV. However, the amino acid sequence of COVID-19 differs from other coronaviruses specifically in the regions of 1ab polyprotein and surface glycoprotein or S-protein. Although several animals have been speculated to be a reservoir for COVID-19, no animal reservoir has been already confirmed. COVID-19 causes COVID-19 disease that has similar symptoms as SARS-CoV. Studies suggest that the human receptor for COVID-19 may be angiotensin-converting enzyme 2 (ACE2) receptor similar to that of SARS-CoV. The nucleocapsid (N) protein of COVID-19 has nearly 90% amino acid sequence identity with SARS-CoV. The N protein antibodies of SARS-CoV may cross react with COVID-19 but may not provide cross-immunity. In a similar fashion to SARS-CoV, the N protein of COVID-19 may play an important role in suppressing the RNA interference (RNAi) to overcome the host defense. This mini-review aims at investigating the most recent trend of COVID-19.
DOI: 10.26355/eurrev_202002_20378
PubMed: 32141569
Affiliations:
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Kannan</name><affiliation wicri:level="1"><nlm:affiliation>School of Medicine, The Maldives National University, Male', Maldives. Kannan.subbaram@mnu.edu.mv.</nlm:affiliation><country xml:lang="fr">Maldives</country><wicri:regionArea>School of Medicine, The Maldives National University, Male'</wicri:regionArea><wicri:noRegion>Male'</wicri:noRegion></affiliation></author><author><name sortKey="Shaik Syed Ali, P" sort="Shaik Syed Ali, P" uniqKey="Shaik Syed Ali P" first="P" last="Shaik Syed Ali">P. Shaik Syed Ali</name></author><author><name sortKey="Sheeza, A" sort="Sheeza, A" uniqKey="Sheeza A" first="A" last="Sheeza">A. Sheeza</name></author><author><name sortKey="Hemalatha, K" sort="Hemalatha, K" uniqKey="Hemalatha K" first="K" last="Hemalatha">K. Hemalatha</name></author></analytic><series><title level="j">European review for medical and pharmacological sciences</title><idno type="eISSN">2284-0729</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Betacoronavirus (chemistry)</term><term>Betacoronavirus (genetics)</term><term>Betacoronavirus (metabolism)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (epidemiology)</term><term>Genome, Viral</term><term>Humans</term><term>Nucleocapsid Proteins (chemistry)</term><term>Nucleocapsid Proteins (genetics)</term><term>Nucleocapsid Proteins (metabolism)</term><term>Pneumonia, Viral (diagnosis)</term><term>Pneumonia, Viral (epidemiology)</term><term>Virus Activation</term><term>World Health Organization</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Activation virale</term><term>Animaux</term><term>Génome viral</term><term>Humains</term><term>Infections à coronavirus (diagnostic)</term><term>Infections à coronavirus (épidémiologie)</term><term>Organisation mondiale de la santé</term><term>Pneumopathie virale (diagnostic)</term><term>Pneumopathie virale (épidémiologie)</term><term>Protéines nucléocapside ()</term><term>Protéines nucléocapside (génétique)</term><term>Protéines nucléocapside (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Nucleocapsid Proteins</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Betacoronavirus</term><term>Nucleocapsid Proteins</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines nucléocapside</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Betacoronavirus</term><term>Nucleocapsid Proteins</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Protéines nucléocapside</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Genome, Viral</term><term>Humans</term><term>Virus Activation</term><term>World Health Organization</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Activation virale</term><term>Animaux</term><term>Génome viral</term><term>Humains</term><term>Organisation mondiale de la santé</term><term>Protéines nucléocapside</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The World Health Organization (WHO) has issued a warning that, although the 2019 novel coronavirus (COVID-19) from Wuhan City (China), is not pandemic, it should be contained to prevent the global spread. The COVID-19 virus was known earlier as 2019-nCoV. As of 12 February 2020, WHO reported 45,171 cases and 1115 deaths related to COVID-19. COVID-19 is similar to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) virus in its pathogenicity, clinical spectrum, and epidemiology. Comparison of the genome sequences of COVID-19, SARS-CoV, and Middle East Respiratory Syndrome coronavirus (MERS-CoV) showed that COVID-19 has a better sequence identity with SARS-CoV compared to MERS CoV. However, the amino acid sequence of COVID-19 differs from other coronaviruses specifically in the regions of 1ab polyprotein and surface glycoprotein or S-protein. Although several animals have been speculated to be a reservoir for COVID-19, no animal reservoir has been already confirmed. COVID-19 causes COVID-19 disease that has similar symptoms as SARS-CoV. Studies suggest that the human receptor for COVID-19 may be angiotensin-converting enzyme 2 (ACE2) receptor similar to that of SARS-CoV. The nucleocapsid (N) protein of COVID-19 has nearly 90% amino acid sequence identity with SARS-CoV. The N protein antibodies of SARS-CoV may cross react with COVID-19 but may not provide cross-immunity. In a similar fashion to SARS-CoV, the N protein of COVID-19 may play an important role in suppressing the RNA interference (RNAi) to overcome the host defense. This mini-review aims at investigating the most recent trend of COVID-19.</div></front></TEI><affiliations><list><country><li>Maldives</li></country></list><tree><noCountry><name sortKey="Hemalatha, K" sort="Hemalatha, K" uniqKey="Hemalatha K" first="K" last="Hemalatha">K. Hemalatha</name><name sortKey="Shaik Syed Ali, P" sort="Shaik Syed Ali, P" uniqKey="Shaik Syed Ali P" first="P" last="Shaik Syed Ali">P. Shaik Syed Ali</name><name sortKey="Sheeza, A" sort="Sheeza, A" uniqKey="Sheeza A" first="A" last="Sheeza">A. Sheeza</name></noCountry><country name="Maldives"><noRegion><name sortKey="Kannan, S" sort="Kannan, S" uniqKey="Kannan S" first="S" last="Kannan">S. Kannan</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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